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Table 1 General characteristics of the included studies

From: Influence of the metabolic and inflammatory profile in patients with frozen shoulder – systematic review and meta-analysis

Author

Year

Study Design

Country

Biomarker

Sample

Gender

Age (years)

Salek et al. [27]

2010

Case-control

Dhakar

Metabolism

FSG = 30

CG = 30

Male and female

FSG = 56.77 ± 8.07

CG = 56.77 ± 8.07

Kabbabe et al. [28]

2010

Case-control

Australia

Inflammation

Gfs = 13

Gc = 10

Male and female

Not specified

Xu et al. [29]

2012

Basic science study, Molecular Biology

Australia

Inflammation

FSG = 8

RTCG = 10

Male and female

FSG = 58 ± 2.25

RTCG = 51 ± 12.5

Kim et al. [30]

2013

Basic science study, Molecular Biology

Korea

Inflammation

FSG = 13

CG = 6

Male and Female

FSG = 52.6 ± 7.25

CG = 40.1 ± 9.75

Lubis et al. [31]

2013

Biology

Indonesia

Inflammation

FSG = 50

CG = 50

Male AND female

FSG = 49.5 ± 10

CG = 53.5 ± 6

Lho et al. [32]

2013

Basic science study, molecular and cell

Korea

Inflammation

GFS = 14

GC = 7

Male AND female

 Not specified

Sung et al. [33]

2014

Case-control

Korea

Metabolism

Fsg = 300

Gc = 900

Male AND female

FSG = 54.01 ± 8.4

CG = 54.01 ± 8.47

Schiefer et al.[34]

2017

Case-control

Brazil

Metabolism

FSG = 93

CG = 151

Male and female

FSG = 56.26 ± 8.61

CG = 52.32 ± 17.23

Safran et a l[35]

2017

Case series

Israel

Metabolism

GFS = 50

Male and Female

FSG = 51 ± 5.4

Chan et al. [36]

2017

Case series, prognosis

USA

METABOLISM

FSG = 197

CG = 4795

Male and female

FSG = 62.0 ± 18.8

CG = 62.0 ± 18.8

Chen A et al. [37]

2017

Case-control

UK

Inflammation

FSG = 42

CG = 50

Male and female

FSG = 53.86 ± 1.60

CG = 54.80 ± 2.58

Yano et al. [38]

2020

Basic Science; Molecular and Cell Biology

Japan

Inflammation

FSG = 33

RCTG = 25

Male and female

FSG: 62.0 ± 7.3

RCTG: 56.4 ± 5.8

Park et al. [39]

2020

Prognostic study: case and control

Korea

Metabolism

FSG = 151

CG = 453

Male and female

FSG = 52.1 ± 7.2

CG = 52.1 ± 7.2

Mertens et al. [40]

2024

Cross-sectional

Belgium

Metabolism

FSG = 35

CG = 35

Male and female

FSG = 53.40 ± 8.95

CG = 52.60 ± 6.93

Chen B et al. [41]

2024

Mendelian randomization

China

Metabolism

FSG = 28,416 (Biobank samples)

Male and Female

* As biobank samples, there is no age limit*

  1. Abbreviations: FSG Frozen Shoulder Group, CG Control Group, RTCG Rotator Cuff, RCTG Rotator Cuff Tear. Age is expressed as mean ± standard deviation