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Table 6 Diagnostic accuracy of combined components of the bedside neurological examination to detect cervical radiculopathy

From: Neurological examination for cervical radiculopathy: a scoping review

Author (year)

Cervical radiculopathy diagnostic criteria

Reference standard

nerve root level/dermatomal territory

Index test

Sensitivity (95% CI)

Specificity (95% CI)

+ LR

- LR

Hassan (2013)

clinical suspicion

Needle EMG and NCS (motor and sensory)

NA

Combination of 2 components

    
    

Sensory loss & tendon reflex loss

14 (5–16)

99 (94–100)

14

0.87

    

Sensory loss & weakness

21 (9–28)

96 (91–99)

5.25

0.82

    

Tendon reflex loss & weakness

22 (11–24)

99 (94–100)

22

0.79

    

Full neurological examination

14 (5–16)

99 (95–100)

14

0.87

Lauder (2000)

neck and upper-limb symptoms, confirmed by EDX

Needle EMG and NCS (motor and sensory)

NA

Combination of 2 components

    
    

Sensory loss & tendon reflex loss

9 (NR)

97 (NR)

3

0.94

    

Sensory loss & weakness

27 (NR)

74 (NR)

1.04

0.99

    

Tendon reflex loss & weakness

18 (NR)

98 (NR)

9

0.84

    

Full neurological examination

7 (NR)

98 (NR)

3.5

0.95

    

Any components

84 (NR)

31 (NR)

1.22

0.52

Inal (2013)

Clinical suspicion

Needle EMG and NCS (motor and sensory)

NA

Full neurological examination

83 (52–98)

28 (13–47)

1.15

0.61

Conradie (2006)

Diagnosis of CR confirmed by MRI

MRI

NA

Full neurological examination

91 (70–99)

   
  1. + LR = positive likelihood ratio; -LR = negative likelihood ratio; 95% CI = 95% confidence interval; EMG = electromyography; NCS = nerve conduction study; MRI = magnetic resonance imaging; CR = Cervical Radiculopathy; NR = Not Reported; NA = Not Applicable