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Table 5 Diagnostic accuracy of muscle function testing to detect cervical radiculopathy

From: Neurological examination for cervical radiculopathy: a scoping review

Author (year)

Cervical radiculopathy diagnostic criteria

Reference standard

nerve root level/dermatomal territory

Index test

Sensitivity (95% CI)

Specificity (95% CI)

+ LR

- LR

Hassan (2013)

Clinical suspicion

Needle EMG and NCS (motor and sensory)

NA

Muscle function testing

54 (38–65)

93 (85–97)

7.71

0.49

Lauder (2000)

Neck and upper-limb symptoms, confirmed by EDX

Needle EMG and NCS (motor and sensory)

NA

Muscle function testing

73 (NR)

61 (NR)

1.87

0.44

Wainner (2003)

Clinical suspicion

Needle EMG and NCS (motor and sensory)

C5

Deltoid

24 (3–44)

89 (81–97)

2.1

0.86

   

C6

Biceps brachii

24 (3–44)

94 (88–100)

3.7

0.82

   

C7

Extensor carpi radialis longus/brevis

12 (0–27)

90 (83–98)

1.2

0.98

   

C7

MMT triceps brachii

12 (0–27)

94 (88–100)

1.9

0.94

   

C8

Flexor carpi radialis

6 (0–17)

89 (82–97)

0.55

1.05

   

T1

Abductor pollicus brevis

6 (0–17)

84 (75–93)

0.37

1.12

   

T1

First dorsal interosseus

3 (0–10)

93 (87–99)

0.40

1.05

Sleijser-Koehorst (2021)

Clinical suspicion

MRI

NA

Muscle function testing

30 (20–43)

72 (60–82)

1.05

0.94

Conradie (2006)

Diagnosis of CR confirmed by MRI

MRI

NA

Muscle function testing

81 (58–95)

   
  1. + LR = positive likelihood ratio; -LR = negative likelihood ratio; 95% CI = 95% confidence interval; EMG = electromyography; NCS = nerve conduction study; MRI = magnetic resonance imaging; CR = Cervical Radiculopathy; NR = Not Reported; NA = Not Applicable