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Table 4 Responsiveness (SRM) of standard cartilage MOAKS scores, Q-MOAKS ratios and quantitative cartilage thickness at one-year and two-year follow-up. Note: ThCtAB SRMs are negative due to loss of cartilage whereas score and ratio changes are positive

From: A comparison of quantitative and semi-quantitative methods for assessing cartilage status and change over time; data from the osteoarthritis initiative

 

YEAR ONE YEAR TWO

ThMCM

ThQCM%

ThCtAB

ThMCM

ThQCM%

ThCtAB

   

FEMUR

  

MOAKS

Q-MOAKS

Thickness

MOAKS

Q-MOAKS

Thickness

cMF

0.15

(0.02, 0.27)

0.36

(0.25, 0.47)

-0.32

(-0.44, -0.20)

0.47

(0.41, 0.54)

0.73

(0.64, 0.83)

-0.84

(-0.96, -0.73)

cLF

0.00

(-0.11, 0.12)

0.09

(-0.04, 0.18)

-0.03

(-0.14, 0.08)

0.11

(0.00, 0.18)

0.24

(0.17, 0.31)

-0.22

(-0.32, -0.11)

pMF

0.21

(0.11, 0.29)

0.18

(0.06, 0.31)

-0.07

(-0.19, 0.04)

0.46

(0.39, 0.53)

0.41

(0.33, 0.51)

-0.37

(-0.48, -0.28)

pLF

0.06

(0.00, 0.10)

0.09

(-0.03, 0.17)

0.02

(-0.09, 0.15)

0.08

(0.00, 0.12)

0.18

(0.11, 0.26)

-0.20

(-0.30, 0.08)

    

TIBIA

  

MOAKS

Q-MOAKS

Thickness

MOAKS

Q-MOAKS

Thickness

cMT

0.16

(0.05, 0.26)

0.28

(0.18, 0.38)

-0.40

(-0.52, -0.30)

0.39

(0.33, 0.45)

0.49

(0.38, 0.60)

-0.73

(-0.85, -0.62)

cLT

0.03

(-0.07, 0.16)

0.14

(0.04, 0.24)

-0.23

(-0.34, -0.13)

0.19

(0.14, 0.25)

0.22

(0.12, 0.32)

-0.47

(-0.59, -0.36)

pMT

0.06

(-0.06, 0.16)

0.22

(0.15, 0.30)

-0.19

(-0.32, 0.08)

0.19

(0.12, 0.24)

0.38

(0.30, 0.45)

-0.48

(-0.56, -0.34)

pLT

-0.06

(-0.13, 0.06)

0.09

(-0.02, 0.20)

-0.21

(-0.31, -0.10)

-0.04

(-0.13, 0.10)

0.23

(0.12, 0.34)

-0.52

(-0.63, -0.42)

aMT

0.15

(0.07, 0.21)

0.13

(0.01, 0.24)

-0.09

(-0.21, 0.03)

0.31

(0.24, 0.38)

0.28

(0.17, 0.39)

-0.34

(-0.45, -0.23)

aLT

n/a

-

-0.03

(-0.13, 0.10)

-0.06

(-0.17, 0.05)

n/a

-

0.13

(0.04, 0.20)

-0.33

(-0.43, -0.23)

  1. Values are SRM (95% CI)