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Table 3 Independent prognostic clinical factors screening

From: Construction and evaluation of a prognostic model based on the expression of the metabolism-related signatures in patients with osteosarcoma

Clinical characteristics

TCGA(N = 176)

Uni-variables cox

Multi-variables cox

HR

95%CI

P

HR

95%CI

P

Age(years,mean ± sd)

61.10 ± 15.21

1.018

1.001–1.036

3.99E-02

1.029

1.006–1.053

1.28E-02

Gender(Male/Female)

72/104

1.061

0.642–1.750

8.20E-01

-

-

-

Pathologic tumor depth(mean ± sd)

6.35 ± 3.68

1.135

1.051–1.225

9.96E-04

1.104

0.934–1.305

2.45E-01

Pathologic tumor length(mean ± sd)

11.89 ± 7.25

1.062

1.031–1.093

3.91E-05

1.089

0.967–1.225

1.60E-01

Pathologic tumor width(mean ± sd)

8.85 ± 5.51

1.092

1.043–1.144

1.37E-04

0.947

0.805–1.113

5.07E-01

Tumor recurrence(Yes/No/-)

28/141/7

2.603

1.533–4.422

2.38E-04

0.905

0.402–2.040

8.10E-01

Tumor metastatic(Yes/No)

56/120

3.014

1.834–4.954

4.80E-06

3.869

1.901–7.874

1.91E-04

Radiotherapy(Yes/No/-)

64/110/2

0.865

0.517–1.447

5.80E-01

-

-

-

Tumor necrosis(No/Slight/Moderate/Severe/-)

61/35/59/11/10

1.182

0.923–1.513

1.83E-01

-

-

-

PS model status(High/ Low)

88/88

5.126

2.890- 9.090

8.74E-10

5.579

2.618–11.889

8.49E-06

Dead(Death/Alive/-)

64/112

-

-

-

-

-

-

Overall survival time(months,mean ± sd)

39.45 ± 31.92

-

-

-

-

-

-